教授-研究员

李 赛

发布时间 :2018年07月12日      阅读量:

    李赛教授-简介

    Mobil: 13628050176 ; Email:lisai@scu.edu.cn

    个人简历

    1994.09~1998.07四川大学,获高分子材料科学与工程学士学位

    1998.09~2001.07四川大学,获生物医学工程硕士学位

    2001.09~2004.07中国科学院成都有机化学研究所,获有机化学博士学位

    2005.02~2007.06新加坡南洋理工大学(博士后)

    2007.07至今四川大学化学化工学院;

    主要研究方向:

    功能高分子材料的合成和加工技术;

    生物医用高分子材料,靶向药物控制缓释;

    新型蒸汽热泵技术;

    发表的主要论文:

    1.Xiang, Hongzhao;Sun, Qiaomei;Wang, Wenjing;Li, Sai*;Xiang, Xi;Li, Zhiqiang;Liao, Xiaoxiang;Li, HuiStudy of conformational and functional changes caused by binding of environmental pollutant tonalide to human serum albumin,Chemosphere,2021,270,129431-42

    2.Zhang, H ;Yan, JQ ;Mei, H ;Cai, SS;Li, S* ;Cheng, FR;Cao, J;He, B,High-drug-loading capacity of redox-activated biodegradable nanoplatform for active targeted delivery of chemotherapeutic drugs,REGENERATIVE BIOMATERIALS2020,7: 4,359-369

    3.Zhang, M;Zhang, XQ;Cai, SS;Mei, H;He, YM ;Huang,;Shi, WQ ;Li,S* ;Cao, J;He, B,Photo-induced specific intracellular release EGFR inhibitor from enzyme/ROS-dual sensitive nano-platforms for molecular targeted-photodynamic combinational therapy of non-small cell lung cancer,JOURNAL OF MATERIALS CHEMISTRY B,2020,8,35, ‏7931-7940;

    4.Wan, SY;Zhang, BY ;Li, S* ;He, B;Pu, YJ,Combination of PEG-decorated black phosphorus nanosheets and immunoadjuvant for photoimmunotherapy of melanoma,JOURNAL OF MATERIALS CHEMISTRY B,,2020, 8,19, 4357, 2805-2813;

    5.Zhao,Mingying;Wan,Shiyu;Peng,Xinyu;Zhang, BY ;Pan, QQ;Li,S* ;He, B ;Pu, YJ.Leveraging a polycationic polymer to direct tunable loading of an anticancer agent and photosensitizer with opposite charges for chemo-photodynamic therapy,JOURNAL OF MATERIALS CHEMISTRY B,2020, 8, 6, 1235-1244

    6.Zhang, BY;Wan, SY;Peng, XY;Zhao, MY;Li, S;Pu, YJ ;He, B,Human serum albumin-based doxorubicin prodrug nanoparticles with tumor pH-responsive aggregation-enhanced retention and reduced cardiotoxicity,JOURNAL OF MATERIALS CHEMISTRY B,2020,8, 17,3939-39482019,

    7. Peng, XY ; Pan, QQ ; Zhang, BY; Wan, SY ; Li, S; Luo, K; Pu, YJ ; He, B,Highly Stable, Coordinated Polymeric Nanoparticles Loading Copper(II) Diethyldithiocarbamate for Combinational Chemo/Chemodynamic Therapy of Cancer,BIOMACROMOLECULES,2019,20 : 6 : 2372-2383

    8. Zhou, Z ; Yuan, ZW ; Li, S ; Li, H; Wang, YQ ; Huang, QW ; Wang, C; Karahan, HE ; Henkelman, Big to Small: Ultrafine Mo2C Particles Derived from Giant Polyoxomolybdate Clusters for Hydrogen Evolution Reaction,SMALL,,2019: 15 : 1-11

    9. X. Q. Zhang, S. S. Cai, Y. M. He, M. Zhang, J. Cao, H. Mei, S. Li and B. He,Enzyme-triggered deshielding of nanoparticles and positive-charge mediated lysosomal escape for chemo/photo-combination therapy,Journal of Materials Chemistry B,2019, 7, 4758--4762

    10. Yixin Zhang, Song Luo, Yan Liang, Hai Zhang, Xinyu Peng,Bin He and Sai Li*, Synthesis, characterization, and property of biodegradable PEG-PCL-PLA terpolymers with miktoarm star andtriblock architectures as drug,Journal of Biomaterials Applications,2018,32,1139-1152

    11. Xu, L ; Yang, ; Zhao, MY ; Gao, WX ; Zhang, H ; Li, S ; He, B ; Pu, YJ A reactive oxygen species-responsive prodrug micelle with efficient cellular uptake and excellent bioavailability,Synthesis and crystallization of well-defined biodegradable mikto arm star PEG-PCL-PLLA,JOURNAL OF MATERIALS CHEMISTRY B,2018,6,1076-1084

    12. F. R. Cheng, Y. Chen, T. Su, H. Cao, S. Li, J. Cao, B. He, Z. W. Gua and X. L. Luo,Intracellular pH-induced fluorescence used to track nanoparticles in cells.J. Mater. Chem. B,2015,3, 5411-5414

    13. Song Luo, Yixin Zhang, Jun Cao, Bin He, Sai Li*,Arginine Modified Polymeric Micelles as a Novel Drug Delivery System with Enhanced Endocytosis Efficiency,Colloids and Surfaces B: Biointerfaces2016, 7,15-23

    14.Song Luo, Xinyu Peng, Ying Chen, Ting Su, Jun Cao, Sai Li* and Bin He,Synthesis, characterization, and crystallization of biodegradable poly(ε-caprolactone)-poly(L-lactide) diblock copolymers.E-polymers. 2015;15:15-23.

    15.Yuanlin Li, Ting Su, Sai Li,* Yusi Lai, Bin He and Zhongwei Gu,Polymeric micelles with π–π conjugated moietyon glycerol dendrimer as lipophilic segments for anticancer drug delivery,Biomaterials Science,2014,2,775-783.

    16.Hui Zheng , Sai Li∗, Yuji Pu a, Yusi Lai a, Bin He , , Zhongwei Gu,Nanoparticles Generated by PEG-Chrysin Conjugates for Efficient Anticancer Drug Delivery,EUR J PHARM BIOPHARM2014,87,454-460.

    17.Shangfeng Pan, Song Luo, Sai Li,* Yusi Lai,a Yanyan Geng, Bin He* and Zhongwei Gu,Ultrasound accelerated gelation of novel l-lysine based hydrogelators,Chemical Communications2013.49.8045-8047

    18.Ying Lei , Yusi Lai , Yuanlin Li , Sai Li ,∗, Gang Cheng, Dong Lia, Haiping Li ,Bin He,∗, Zhongwei Gu,Anticancer drug delivery of PEG based micelles with small lipophilic moieties.International Journal of pharmaceutics,2013.453.579-586

    19.Jun Cao, Aijing Lua, Chenglong Li , Mengtan Cai, Yuanwei Chen,Sai Li ,∗, Xianglin Luo Effect of architecture on the micellar properties of poly( -caprolactone) containing sulfobetaines,Colloids and Surfaces B Biointerfaces,2013,112,35-41

    20.Danna Yang, Lin Wang, Qiang Zhao, Sai Li*,Fabrication Of Single-Walled Carbon Nanotubes (SWNTs) Field-Effect Transistor (FET) Biosensor 2010 3RD INTERNATIONAL CONFERENCE ON BIOMEDICAL ENGINEERING AND INFORMATICS (BMEI 2010), VOLS 1-7 ,1482-1485

    21.Danna Yang, Lin Wang, Xiaoxian Zhang, Dongwei Wang, Zhiqiang Shen, Sai Li*, Alignment of Nanoscale Single-Walled Carbon Nanotubes Strands,NANO-MICRO LETTERS(3)3 ,146-152, 2011

    22.Wang, Dongwei; Zhang, Xiaoxian; Yang, Danna,Li Sai*, Study of Preparation and Properties of Fire-retardant Melamine Formaldehyde Resin Foam Advanced Materials Research No .510, 634-638.2012

    23.Sai Li, Yehai Yan, Ningyi Liu, Mary B. Chan-Park,* and Qing Zhang,Transfer Printing of Sub-Micron Patterns of Aligned Carbon Nanotubes onto Functionalized ElectrodesSmall3, No. 4, 6 16 – 621,2007,

    24. Sai Li, Ningyi Liu, Mary B Chan-Park, Yehai Yan, and Qing Zhang,Aligned Single-Walled Carbon Nanotube Patterns with Nanoscale Widths, Micronscale Lengths and Controllable Pitch,Nanotechnology18, 455302-455309.2007

    获奖及发明专利

    PCT/CN106765049B蒸气热泵及低压蒸气补焓增压利用的方法

    个人奖励:

    ●2009、2014年获四川大学青年骨干教师奖

    ●2012、2016获全国化工设计大赛金奖指导老师

    ●2012、2013,2016、2020年度四川大学课堂教学质量优秀奖

    ●2012、2013、2014年大学生课外科技实践优秀指导教师奖

    ●2016年度四川大学唐立新教学名师奖

    ●2017年度四川大学圣华曦奖

    2018年度四川省教学成果二等奖

    ●2019年度四川大学星火校友奖

    论著

    1、《近代化学基础》(国家面向21世纪课程教材)第三版下册,高等教育出版社出版,2015,

    2、《工科物理化学教程》(国家十二五规划教材),第三版,科学出版社,2012,




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